manuscript

adj

1. (not-comparable)Handwritten, or by extension manually typewritten, as opposed to being mechanically reproduced.

noun

1. A book, composition or any other document, written by hand (or manually typewritten), not mechanically reproduced.

   “In the old days, to my commonplace and unobserving mind, he gave no evidences of genius whatsoever. He never read me any of his manuscripts, […], and therefore my lack of detection of his promise may in some degree be pardoned.”

   “The ability of a segment of a glass sphere to magnify whatever is placed before it was known around the year 1000, when the spherical segment was called a reading stone,[…]. Scribes, illuminators, and scholars held such stones directly over manuscript pages as an aid in seeing what was being written, drawn, or read.”

   “The [Isaac] Newton that emerges from the [unpublished] manuscripts is far from the popular image of a rational practitioner of cold and pure reason. The architect of modern science was himself not very modern. He was obsessed with alchemy.”

2. A single, original copy of a book, article, composition etc, written by hand or even printed, submitted as original for (copy-editing and) reproductive publication.