motexafin

noun

1. an inhibitor of thioredoxin reductase and ribonucleotide reductase

   “The meta-analysis of Qin et al [12 ] confirmed that the combination of WBRT plus chemotherapy (including TMZ, carboplatin, and motexafin gadolinium) may increase treatment response rates in patients with BM, therefore TMZ combined with RT can be a reasonable treatment option for patients with BM. However, follow-up studies conclude that the addition of TMZ to RT does not improve survival and has an increased incidence of adverse events compared with RT alone [13 ,14 ].”