stupefy

verb

1. (especially, transitive)To dull the senses or capacity to think thereby reducing responsiveness; to stun.

   “a stupefying drug; a stupefacient”

   “He stupefied her by means of chloroform, a general anaesthetic.”

2. (broadly, figuratively, transitive)To astonish or stun, especially as a result of some distressing action.

   “The police's negligence and callousness continued to stupefy her.”

   “What if I love you!—This misery / Of your dissatisfaction and misprision / Stupefies me.”

3. (obsolete, transitive)To deprive a material of the ability to undergo change or movement, especially deformation.

   “The next is, when it is not malleable, but yet it is not fluent, but stupified^([sic]).”